BDBM50304624 CHEMBL4174055

SMILES CC1(NC(=O)N(CC(O)CN2CCN(CC2)c2ccccc2C#N)C1=O)c1ccc(Cl)cc1

InChI Key InChIKey=KPTJFDAGYOHPFI-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50304624   

Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50304624(CHEMBL4174055)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-5-CT from human 5HT7BR expressed in HEK293 cell membranes after 1 hr by Microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50304624(CHEMBL4174055)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]-prazosin from alpha1-adrenergic receptor in rat brain cortex after 30 mins by Microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50304624(CHEMBL4174055)
Affinity DataKi:  305nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1AR expressed in HEK293 cell membranes after 1 hr by Microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50304624(CHEMBL4174055)
Affinity DataKi:  1.29E+3nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cell membranes after 1 hr by Microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50304624(CHEMBL4174055)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-CGP-12177 from beta1-adrenergic receptor in rat brain cortex after 1 hr by Microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2020
Entry Details Article
PubMed
LigandPNGBDBM50304624(CHEMBL4174055)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-clonidine from alpha2-adrenergic receptor in rat brain cortex after 30 mins by Microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2020
Entry Details Article
PubMed