BDBM50304897 (S)-3-(5-((1-acetylindolin-2-yl)methoxy)-3-(tert-butylsulfonyl)-1-(4-chlorobenzyl)-1H-indol-2-yl)-2,2-dimethylpropanoic acid::CHEMBL610471

SMILES CC(=O)N1[C@H](COc2ccc3n(Cc4ccc(Cl)cc4)c(CC(C)(C)C(O)=O)c(c3c2)S(=O)(=O)C(C)(C)C)Cc2ccccc12

InChI Key InChIKey=WHLUEMFKZGNWOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304897   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50304897((S)-3-(5-((1-acetylindolin-2-yl)methoxy)-3-(tert-b...)
Affinity DataIC50: 4.5nMAssay Description:Binding affinity to FLAP in human PMN derived membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed