BDBM503052 N-[2-(1-benzylpiperidin-4-yl)ethyl]-1-[3-chloro-5 (trifluoromethyl)pyridin-2-yl]piperidine-4-carboxamide::US11033539, Cpd. No. 9-63

SMILES FC(F)(F)c1cnc(N2CCC(CC2)C(=O)NCCC2CCN(Cc3ccccc3)CC2)c(Cl)c1

InChI Key InChIKey=UCDAGGLRRYYIRU-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 503052   

TargetMuscarinic acetylcholine receptor M4(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM503052(US11033539, Cpd. No. 9-63 | N-[2-(1-benzylpiperidi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM503052(US11033539, Cpd. No. 9-63 | N-[2-(1-benzylpiperidi...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM503052(US11033539, Cpd. No. 9-63 | N-[2-(1-benzylpiperidi...)
Affinity DataKi:  55nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM503052(US11033539, Cpd. No. 9-63 | N-[2-(1-benzylpiperidi...)
Affinity DataKi:  55nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M5(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM503052(US11033539, Cpd. No. 9-63 | N-[2-(1-benzylpiperidi...)
Affinity DataKi:  550nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent