BDBM50305264 8-Methoxy-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole::CHEMBL589389

SMILES COc1ccc2n(CCc3ccccc3)c3CCN(C)Cc3c2c1

InChI Key InChIKey=JGJNEIOIBJGSFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305264   

TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305264(8-Methoxy-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-...)
Affinity DataIC50: 104nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305264(8-Methoxy-2-methyl-5-phenethyl-2,3,4,5-tetrahydro-...)
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed