BDBM50305269 5-[2-(4-Methoxyphenyl)ethyl]-2,8-dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole::CHEMBL589147

SMILES COc1ccc(CCn2c3CCN(C)Cc3c3cc(C)ccc23)cc1

InChI Key InChIKey=IJQSFAYWVZPICY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305269   

TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305269(5-[2-(4-Methoxyphenyl)ethyl]-2,8-dimethyl-2,3,4,5-...)
Affinity DataIC50: 66nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305269(5-[2-(4-Methoxyphenyl)ethyl]-2,8-dimethyl-2,3,4,5-...)
Affinity DataIC50: 666nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed