BDBM50305270 2,8-Dimethyl-5-[2-(4-trifluoromethylphenyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole::CHEMBL606036

SMILES CN1CCc2c(C1)c1cc(C)ccc1n2CCc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=FCDNLGMRDAOTCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305270   

TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305270(2,8-Dimethyl-5-[2-(4-trifluoromethylphenyl)ethyl]-...)
Affinity DataIC50: 98nMAssay Description:Antagonist activity at histamine H1 receptor in human SK-N-SH cells assessed as histamine-induced maximum intracellular calcium spike at phase 1 trea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50305270(2,8-Dimethyl-5-[2-(4-trifluoromethylphenyl)ethyl]-...)
Affinity DataIC50: 4.07E+3nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced increase in intracellula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed