BDBM50305366 (3aR,6aS)-2-((6-chloropyridin-3-yl)methyl)-5-(6-phenylpyridazin-3-yl)octahydropyrrolo[3,4-c]pyrrole::CHEMBL600054

SMILES Clc1ccc(CN2C[C@H]3CN(C[C@H]3C2)c2ccc(nn2)-c2ccccc2)cn1

InChI Key InChIKey=MHYRUAVUYIIOBC-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305366   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305366((3aR,6aS)-2-((6-chloropyridin-3-yl)methyl)-5-(6-ph...)
Affinity DataEC50:  1.18E+4nMAssay Description:Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes assessed as induction of Ca2+ currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50305366((3aR,6aS)-2-((6-chloropyridin-3-yl)methyl)-5-(6-ph...)
Affinity DataKi:  102nMAssay Description:Displacement of [3H]585539 from alpha7 nAChR in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed