BDBM50305497 (4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinolin-3-yl)methanamine::CHEMBL590584

SMILES CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(CN)cnc3c(cccc23)C(F)(F)F)c1

InChI Key InChIKey=RKGUCTQUPQWZOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305497   

TargetOxysterols receptor LXR-beta(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305497((4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(triflu...)
Affinity DataIC50: 77nMAssay Description:Displacement of [3H]TO901317 from human recombinant LXRbeta expressed in Escherichia coli by flashplate methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50305497((4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(triflu...)
Affinity DataIC50: 445nMAssay Description:Displacement of [3H]TO901317 from human recombinant LXRalpha expressed in Escherichia coli by flashplate methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed