BDBM50305799 5-((3aR,6aS)-5-(2-(1-(3,3-difluorocyclobutanecarbonyl)-3-phenylazetidin-3-yl)ethyl)octahydropyrrolo[3,4-c]pyrrole-2-carbonyl)-4,6-dimethylpicolinonitrile::CHEMBL593042

SMILES Cc1cc(nc(C)c1C(=O)N1C[C@@H]2CN(CCC3(CN(C3)C(=O)C3CC(F)(F)C3)c3ccccc3)C[C@@H]2C1)C#N

InChI Key InChIKey=YDPUJHRXDCRWKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305799   

TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50305799(5-((3aR,6aS)-5-(2-(1-(3,3-difluorocyclobutanecarbo...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50305799(5-((3aR,6aS)-5-(2-(1-(3,3-difluorocyclobutanecarbo...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed