BDBM50305858 CHEMBL605928::trans-4-((5-(2-(4-fluoro-3-methylbenzylcarbamoyl)-6-methylpyridin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylic acid

SMILES Cc1cc(cc(n1)C(=O)NCc1ccc(F)c(C)c1)-c1nnn(C[C@H]2CC[C@@H](CC2)C(O)=O)n1

InChI Key InChIKey=YCYIBGJERWDXNO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305858   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305858(trans-4-((5-(2-(4-fluoro-3-methylbenzylcarbamoyl)-...)
Affinity DataKi:  0.220nMAssay Description:Inhibition of human recombinant full length MMP13 assessed as type 3 collagen cleavage activity after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed