BDBM50306509 4'-((3-(methylthio)-5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid::CHEMBL590983

SMILES CCCc1c(SC)c2cc(NC(=O)C(CC)c3ccccc3)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key InChIKey=YWRCLPWCJQIOPK-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50306509   

TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306509(4'-((3-(methylthio)-5-(2-phenylbutanamido)-2-propy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled GW-2433 from human PPARdelta ligand binding domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306509(4'-((3-(methylthio)-5-(2-phenylbutanamido)-2-propy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled GW-2433 from human PPARalpha ligand binding domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306509(4'-((3-(methylthio)-5-(2-phenylbutanamido)-2-propy...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARdelta expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306509(4'-((3-(methylthio)-5-(2-phenylbutanamido)-2-propy...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306509(4'-((3-(methylthio)-5-(2-phenylbutanamido)-2-propy...)
Affinity DataIC50: 36nMAssay Description:Displacement of radiolabeled ((5-{4-[Methyl-pyridin-2yl-amino)-ethoxy]-benzyl}-thiazolidine-2,4-dione) from human PPARgamma ligand binding domain exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306509(4'-((3-(methylthio)-5-(2-phenylbutanamido)-2-propy...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed