BDBM50306510 4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid::CHEMBL601222

SMILES CCCc1cc2cc(NC(=O)C(CC)c3ccccc3)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key InChIKey=WRKLSZQCSKSDIC-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50306510   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306510(4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306510(4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl...)
Affinity DataIC50: 260nMAssay Description:Displacement of radiolabeled ((5-{4-[Methyl-pyridin-2yl-amino)-ethoxy]-benzyl}-thiazolidine-2,4-dione) from human PPARgamma ligand binding domain exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306510(4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled GW-2433 from human PPARdelta ligand binding domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306510(4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled GW-2433 from human PPARalpha ligand binding domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306510(4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed