BDBM50306511 4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid::CHEMBL590984

SMILES CCCc1c(SC)c2ccc(NC(=O)C(CC)c3ccccc3)cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key InChIKey=ZMGXUFQMCWERPK-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50306511   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306511(4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled GW-2433 from human PPARalpha ligand binding domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306511(4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propy...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306511(4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propy...)
Affinity DataIC50: 6.95E+3nMAssay Description:Displacement of radiolabeled GW-2433 from human PPARdelta ligand binding domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306511(4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propy...)
Affinity DataIC50: 490nMAssay Description:Displacement of radiolabeled ((5-{4-[Methyl-pyridin-2yl-amino)-ethoxy]-benzyl}-thiazolidine-2,4-dione) from human PPARgamma ligand binding domain exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306511(4'-((3-(methylthio)-6-(2-phenylbutanamido)-2-propy...)
Affinity DataEC50:  201nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed