BDBM50306512 4'-((2,3-dimethyl-5-(2-phenylbutanamido)-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid::CHEMBL601861

SMILES CCC(C(=O)Nc1ccc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(C)c(C)c2c1)c1ccccc1

InChI Key InChIKey=LZKKDOUXFIOQEM-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50306512   

TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306512(4'-((2,3-dimethyl-5-(2-phenylbutanamido)-1H-indol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled GW-2433 from human PPARdelta ligand binding domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306512(4'-((2,3-dimethyl-5-(2-phenylbutanamido)-1H-indol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radiolabeled GW-2433 from human PPARalpha ligand binding domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306512(4'-((2,3-dimethyl-5-(2-phenylbutanamido)-1H-indol-...)
Affinity DataEC50:  6.14E+3nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306512(4'-((2,3-dimethyl-5-(2-phenylbutanamido)-1H-indol-...)
Affinity DataIC50: 574nMAssay Description:Displacement of radiolabeled ((5-{4-[Methyl-pyridin-2yl-amino)-ethoxy]-benzyl}-thiazolidine-2,4-dione) from human PPARgamma ligand binding domain exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306512(4'-((2,3-dimethyl-5-(2-phenylbutanamido)-1H-indol-...)
Affinity DataEC50:  338nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed