BDBM50306814 CHEMBL601036::rac-6-hydroxy-8-(1-hydroxy-2-(2-methyl-1-o-tolylpropan-2-ylamino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

SMILES Cc1ccccc1CC(C)(C)NCC(O)c1cc(O)cc2NC(=O)COc12

InChI Key InChIKey=IPPHWQIXUDIHFZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306814   

TargetBeta-2 adrenergic receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50306814(rac-6-hydroxy-8-(1-hydroxy-2-(2-methyl-1-o-tolylpr...)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human recombinant adrenergic beta2 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50306814(rac-6-hydroxy-8-(1-hydroxy-2-(2-methyl-1-o-tolylpr...)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human recombinant adrenergic beta-1 receptor expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed