BDBM50307475 (1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-spiro[cyclohexane-1,30-indol]-1'(2'H)-ylpropan-2-ol Hydrochloride::CHEMBL602550

SMILES CNC[C@@H](O)[C@@H](N1CC2(CCCCC2)c2ccccc12)c1cccc(F)c1

InChI Key InChIKey=VSVCFDIMOHRRET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307475   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50307475((1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-spiro...)
Affinity DataIC50: 39nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50307475((1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-spiro...)
Affinity DataIC50: 4.92E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed