BDBM50307532 8-(Cyclohexylamino)-N-1-dimethyl-4,5-dihydro-1H-pyrazolo-[4,3-h]quinazoline-3-carboxamide::CHEMBL591463

SMILES CNC(=O)c1nn(C)c-2c1CCc1cnc(NC3CCCCC3)nc-21

InChI Key InChIKey=SZVPDWROAQYJHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307532   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50307532(8-(Cyclohexylamino)-N-1-dimethyl-4,5-dihydro-1H-py...)
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50307532(8-(Cyclohexylamino)-N-1-dimethyl-4,5-dihydro-1H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed