BDBM50307835 CHEMBL590956::Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate

SMILES Nc1c(cc(Nc2ccc(F)cc2C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O

InChI Key InChIKey=OBFSYBSKXOCXQH-UHFFFAOYSA-M

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50307835   

TargetP2Y purinoceptor 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50307835(Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9...)
Affinity DataIC50: 2.99E+4nMAssay Description:Antagonist activity at human P2Y2 receptor expressed in astrocytoma cells assessed as inhibition of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 4(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50307835(Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2Y4 receptor expressed in astrocytoma cells assessed as inhibition of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 6(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50307835(Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat P2Y6 receptor expressed in astrocytoma cells assessed as inhibition of intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 4(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50307835(Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human P2Y4 receptor transfected in human 1321N1 cells assessed as inhibition of UTP-activated intracellular calcium mobilizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50307835(Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9...)
Affinity DataKi:  260nMAssay Description:Inhibition of rat ecto-5'-nucleotidase expressed in Sf9 cells by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50307835(Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9...)
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition of human NTPdase1 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50307835(Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human NTPdase3 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50307835(Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human NTPdase2 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed