BDBM50308067 4-(4-tert-Butyl-phenyl)-1-isopropyl-6-methoxy-1H-quinazolin-2-one::CHEMBL599868

SMILES COc1ccc2n(C(C)C)c(=O)nc(-c3ccc(cc3)C(C)(C)C)c2c1

InChI Key InChIKey=JPGLJHNGXAZHEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308067   

TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308067(4-(4-tert-Butyl-phenyl)-1-isopropyl-6-methoxy-1H-q...)
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed