BDBM50308086 CHEMBL603248::{4-[4-(4-Isopropyl-phenyl)-2-oxo-6-propargyloxy-2H-quinazolin-1-ylmethyl]-phenoxy}-acetic acid

SMILES CC(C)c1ccc(cc1)-c1nc(=O)n(Cc2ccc(OCC(O)=O)cc2)c2ccc(OCC#C)cc12

InChI Key InChIKey=YGNMYAFGALQODU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308086   

TargetExtracellular calcium-sensing receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50308086({4-[4-(4-Isopropyl-phenyl)-2-oxo-6-propargyloxy-2H...)
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at human CaSR expressed in CCL39 cells assessed as inhibition of extracellular calcium-induced intracellular calcium transient by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed