BDBM50308265 2-{4-[(Benzylmethylamino)methyl]benzylidene}-6-(5-piperidin-1-yl-pentyloxy)indan-1-one::CHEMBL603256

SMILES CN(Cc1ccccc1)Cc1ccc(\C=C2/Cc3ccc(OCCCCCN4CCCCC4)cc3C2=O)cc1

InChI Key InChIKey=MUBGEWUJBWWEGW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50308265   

TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50308265(2-{4-[(Benzylmethylamino)methyl]benzylidene}-6-(5-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins prior to substrate addition by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2016
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50308265(2-{4-[(Benzylmethylamino)methyl]benzylidene}-6-(5-...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human BuChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50308265(2-{4-[(Benzylmethylamino)methyl]benzylidene}-6-(5-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed