BDBM50308554 3-(4-(3-hydroxypropyl)-1,4-diazepan-1-yl)-1-(2-propoxyethyl)-7-(6-methoxypyridin-3-yl)pyrido[3,4-b]pyrazin-2(1H)-one::CHEMBL590787

SMILES CCCOCCn1c2cc(ncc2nc(N2CCCN(CCCO)CC2)c1=O)-c1ccc(OC)nc1

InChI Key InChIKey=PEWZFEYDMCHRJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308554   

LigandPNGBDBM50308554(3-(4-(3-hydroxypropyl)-1,4-diazepan-1-yl)-1-(2-pro...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed