BDBM50308557 3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxyethyl)-7-(6-methoxypyridin-3-yl)pyrido[3,4-b]pyrazin-2(1H)-one::CHEMBL591501

SMILES CCCOCCn1c2cc(ncc2nc(N2CCN(CCO)CC2)c1=O)-c1ccc(OC)nc1

InChI Key InChIKey=MNLNAGRCHNMKKJ-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50308557   

LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE4CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE3BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE1CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PDE1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50308557(3-(4-(2-hydroxyethyl)piperazin-1-yl)-1-(2-propoxye...)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of human ERG by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed