BDBM50308632 1-Butyl-1-(3,5-dichloro-2-hydroxybenzyl)-3-phenylthiourea::CHEMBL591440

SMILES CCCCN(Cc1cc(Cl)cc(Cl)c1O)C(=S)Nc1ccccc1

InChI Key InChIKey=HSYMTXUHTDJFRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308632   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308632(1-Butyl-1-(3,5-dichloro-2-hydroxybenzyl)-3-phenylt...)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of cloned EGFR autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308632(1-Butyl-1-(3,5-dichloro-2-hydroxybenzyl)-3-phenylt...)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of human cloned HER2 autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed