BDBM50308859 3-[3-(3-Chloro-4-cyano-phenyl)-ureidomethyl]-N-(3-dimethylaminomethyl-benzyl)-benzamide::CHEMBL591058

SMILES CN(C)Cc1ccc(NC(=O)c2cccc(CNC(=O)Nc3ccc(C#N)c(Cl)c3)c2)cc1

InChI Key InChIKey=XXLBWBWONGRALC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308859   

TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308859(3-[3-(3-Chloro-4-cyano-phenyl)-ureidomethyl]-N-(3-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308859(3-[3-(3-Chloro-4-cyano-phenyl)-ureidomethyl]-N-(3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed