BDBM50308874 3,4-Dimethoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)-benzyl]-benzamide::CHEMBL598336

SMILES COc1ccc(cc1OC)C(=O)NCc1cccc(c1)C(=O)NCCc1ccncc1

InChI Key InChIKey=JUBQGWGPNRKSSH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50308874   

TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308874(3,4-Dimethoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human CYP3A4 using BQ substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308874(3,4-Dimethoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2C19 by LCMS/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308874(3,4-Dimethoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human CYP2C9 by LCMS/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308874(3,4-Dimethoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP1A2 by LCMS/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308874(3,4-Dimethoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308874(3,4-Dimethoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human ROCK1 by homogenous luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308874(3,4-Dimethoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6 by LCMS/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308874(3,4-Dimethoxy-N-[3-(2-pyridin-4-yl-ethylcarbamoyl)...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human CYP3A4 by LCMS/MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed