BDBM50309193 4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)phenol::CHEMBL604459::US10688093, Compound 382_7249_0087::US11701353, Compound 382_7249_0087

SMILES COc1cc(cc(OC)c1OC)-c1cnc(N)c(c1)-c1ccc(O)cc1

InChI Key InChIKey=BZRTYUHZFBKUNX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50309193   

TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM50309193(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50: 209nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM50309193(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50: 288nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309193(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed