BDBM50309337 10-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]quinazolin-6(2H)-one::CHEMBL590332

SMILES Cc1cccc2C(=O)NC3CNCCN3c12

InChI Key InChIKey=RDKUQQKQJMPPCX-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50309337   

Target5-hydroxytryptamine receptor 2C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309337(10-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qu...)
Affinity DataEC50:  4.20E+3nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309337(10-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qu...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309337(10-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qu...)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [125I]LSD from human recombinant 5HT2B receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309337(10-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qu...)
Affinity DataKi:  6.15E+3nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309337(10-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qu...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed