BDBM50309342 2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7-a]quinazolin-7(1H)-one::CHEMBL590816

SMILES O=C1NC2CCNCCN2c2ccccc12

InChI Key InChIKey=OCAKADOGXISKBY-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50309342   

Target5-hydroxytryptamine receptor 2C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309342(2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7-a]quinaz...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309342(2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7-a]quinaz...)
Affinity DataKi:  49nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309342(2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7-a]quinaz...)
Affinity DataKi:  67nMAssay Description:Displacement of [125I]LSD from human recombinant 5HT2B receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309342(2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7-a]quinaz...)
Affinity DataEC50:  101nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309342(2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7-a]quinaz...)
Affinity DataEC50:  248nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309342(2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7-a]quinaz...)
Affinity DataKi:  269nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed