BDBM50309360 6-(4-(5-((6,7-dichloro-1-oxo-1,2-dihydropyrrolo[1,2-a]pyrazin-4-yl)methyl)-2-fluorobenzoyl)piperazin-1-yl)nicotinonitrile::CHEMBL602752

SMILES Fc1ccc(Cc2c[nH]c(=O)c3cc(Cl)c(Cl)n23)cc1C(=O)N1CCN(CC1)c1ccc(cn1)C#N

InChI Key InChIKey=NIGYPPWMILKYQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309360   

TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50309360(6-(4-(5-((6,7-dichloro-1-oxo-1,2-dihydropyrrolo[1,...)
Affinity DataIC50: 14nMAssay Description:Inhibition of PARP1 by topcount microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed