BDBM50309507 2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine::CHEMBL597530

SMILES Fc1ccccc1Oc1ncccc1C1CCNCC1

InChI Key InChIKey=OTTUCFBNHXCUBH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309507   

Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309507(2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine | C...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniquesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50309507(2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine | C...)
Affinity DataKi:  536nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309507(2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine | C...)
Affinity DataKi:  728nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309507(2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine | C...)
Affinity DataKi: >6.18E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed