BDBM50309516 2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine::CHEMBL598767

SMILES Fc1ccc(Oc2ncccc2C2CCNCC2)c(F)c1

InChI Key InChIKey=GKIYCLAZFANGKD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309516   

Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309516(2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniquesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309516(2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50309516(2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)
Affinity DataKi:  143nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309516(2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)
Affinity DataKi:  2.59E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed