BDBM50309521 2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyridine::CHEMBL599592

SMILES Cc1cccc(F)c1Oc1ncccc1C1CCNCC1

InChI Key InChIKey=MNKYSXOLQYNYNU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309521   

Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309521(2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyr...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniquesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
LigandPNGBDBM50309521(2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyr...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309521(2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyr...)
Affinity DataKi:  102nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309521(2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyr...)
Affinity DataKi: >6.37E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed