BDBM50309677 (2S,6S,2R)-2-[6-(2-Propionyloxy-2-phenylethyl)-1-methylpiperidin-2-yl]-1-phenylethanone hydrochloride::CHEMBL597270

SMILES CCC(=O)O[C@@H](C[C@@H]1CCC[C@H](CC(=O)c2ccccc2)N1C)c1ccccc1

InChI Key InChIKey=OJNUQLKSVMUMID-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50309677   

TargetSynaptic vesicular amine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309677((2S,6S,2R)-2-[6-(2-Propionyloxy-2-phenylethyl)-1-m...)
Affinity DataKi:  4.75E+3nMAssay Description:Displacement of [3H]MTBZ from VMAT2 in rat whole brain vesicles by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309677((2S,6S,2R)-2-[6-(2-Propionyloxy-2-phenylethyl)-1-m...)
Affinity DataKi:  4.87E+3nMAssay Description:Inhibition of [3H]5HT uptake at SERT in rat brain hippocampal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50309677((2S,6S,2R)-2-[6-(2-Propionyloxy-2-phenylethyl)-1-m...)
Affinity DataKi:  6.88E+3nMAssay Description:Inhibition of [3H]DA uptake at DAT in rat brain striatal synaptosomes by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed