BDBM50309927 2-(4-(4-methylpiperazin-1-yl)phenyl)-3-oxoisoindoline-4-carboxamide::CHEMBL598978

SMILES CN1CCN(CC1)c1ccc(cc1)N1Cc2cccc(C(N)=O)c2C1=O

InChI Key InChIKey=CVABBTLWVQVDMB-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309927   

TargetPoly [ADP-ribose] polymerase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50309927(2-(4-(4-methylpiperazin-1-yl)phenyl)-3-oxoisoindol...)
Affinity DataEC50:  22nMAssay Description:Inhibition of PARP1 in human C41 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50309927(2-(4-(4-methylpiperazin-1-yl)phenyl)-3-oxoisoindol...)
Affinity DataKi:  48nMAssay Description:Inhibition of PARP1 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed