BDBM50310807 CHEMBL1078232::N-(4-chlorophenyl)-3-(3-morpholino-3-oxopropyl)-3-phenylpiperidine-1-carboxamide

SMILES Clc1ccc(NC(=O)N2CCCC(CCC(=O)N3CCOCC3)(C2)c2ccccc2)cc1

InChI Key InChIKey=RPEDWPSRPWEPAU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50310807   

TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310807(N-(4-chlorophenyl)-3-(3-morpholino-3-oxopropyl)-3-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310807(N-(4-chlorophenyl)-3-(3-morpholino-3-oxopropyl)-3-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310807(N-(4-chlorophenyl)-3-(3-morpholino-3-oxopropyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310807(N-(4-chlorophenyl)-3-(3-morpholino-3-oxopropyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310807(N-(4-chlorophenyl)-3-(3-morpholino-3-oxopropyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310807(N-(4-chlorophenyl)-3-(3-morpholino-3-oxopropyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nav1.5 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed