BDBM50310815 3-(3-(biphenyl-4-yl)-1-(4-(trifluoromethoxy)phenylcarbamoyl)piperidin-3-yl)propanoic acid::CHEMBL1079061

SMILES OC(=O)CCC1(CCCN(C1)C(=O)Nc1ccc(OC(F)(F)F)cc1)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=WFKBKGKEWUKRGP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50310815   

TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310815(3-(3-(biphenyl-4-yl)-1-(4-(trifluoromethoxy)phenyl...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310815(3-(3-(biphenyl-4-yl)-1-(4-(trifluoromethoxy)phenyl...)
Affinity DataIC50: 413nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310815(3-(3-(biphenyl-4-yl)-1-(4-(trifluoromethoxy)phenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310815(3-(3-(biphenyl-4-yl)-1-(4-(trifluoromethoxy)phenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed