BDBM50311079 (1S,2R)-1-(4'-chlorobiphenyl-4-ylsulfonamido)-2-phenylcyclopropanecarboxylic acid::CHEMBL1079173::US10322143, Shiozaki Compound 4

SMILES OC(=O)[C@@]1(C[C@@H]1c1ccccc1)NS(=O)(=O)c1ccc(cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=RKHASFKRFZMOOJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311079   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Universitetet I Oslo

US Patent
LigandPNGBDBM50311079((1S,2R)-1-(4'-chlorobiphenyl-4-ylsulfonamido)-2-ph...)
Affinity DataIC50: 84nMAssay Description:Protein concentrations were measured using the Micro BCA Protein Assay Kit (Pierce/Thermo Scientific, IL). Sample buffer was mixed with 5-25 μg ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Universitetet I Oslo

US Patent
LigandPNGBDBM50311079((1S,2R)-1-(4'-chlorobiphenyl-4-ylsulfonamido)-2-ph...)
Affinity DataIC50: 84nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed