BDBM50311082 (1S,2R)-1-(5-(5-chloropyridin-2-yl)thiophene-2-sulfonamido)-2-phenylcyclopropanecarboxylic acid::CHEMBL1077892::US10322143, Shiozaki Ciompound 8

SMILES OC(=O)[C@@]1(C[C@@H]1c1ccccc1)NS(=O)(=O)c1ccc(s1)-c1ccc(Cl)cn1

InChI Key InChIKey=NNOZBVKNPNHPKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311082   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311082((1S,2R)-1-(5-(5-chloropyridin-2-yl)thiophene-2-sul...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311082((1S,2R)-1-(5-(5-chloropyridin-2-yl)thiophene-2-sul...)
Affinity DataIC50: 100nMAssay Description:Protein concentrations were measured using the Micro BCA Protein Assay Kit (Pierce/Thermo Scientific, IL). Sample buffer was mixed with 5-25 μg ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent