BDBM50311321 CHEMBL1078745::N-(1-(3-ethoxy-5-(tetrahydro-2H-pyran-4-yloxy)benzyl)piperidin-4-yl)benzo[d]oxazol-2-amine

SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3ccccc3o2)cc(OC2CCOCC2)c1

InChI Key InChIKey=FDVIZOQPGHRQNB-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50311321   

Target5-hydroxytryptamine receptor 2B(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311321(N-(1-(3-ethoxy-5-(tetrahydro-2H-pyran-4-yloxy)benz...)
Affinity DataKi:  94nMAssay Description:Binding affinity to human 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311321(N-(1-(3-ethoxy-5-(tetrahydro-2H-pyran-4-yloxy)benz...)
Affinity DataKi:  199nMAssay Description:Displacement of SST14 from human recombinant SST5 receptor expressed in CHO cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311321(N-(1-(3-ethoxy-5-(tetrahydro-2H-pyran-4-yloxy)benz...)
Affinity DataKi:  3.60E+3nMAssay Description:Binding affinity to human histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311321(N-(1-(3-ethoxy-5-(tetrahydro-2H-pyran-4-yloxy)benz...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of SST14 from human recombinant SST3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311321(N-(1-(3-ethoxy-5-(tetrahydro-2H-pyran-4-yloxy)benz...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of SST14 from human recombinant SST4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311321(N-(1-(3-ethoxy-5-(tetrahydro-2H-pyran-4-yloxy)benz...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of SST14 from human recombinant SST2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed