BDBM50311348 CHEMBL1079313::N-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-yl)-5-(ethylsulfonyl)benzo[d]oxazol-2-amine

SMILES CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)S(=O)(=O)CC)ccc1OC

InChI Key InChIKey=KLQBJPKPQBLAOR-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311348   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311348(N-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-yl)-5-(...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311348(N-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-yl)-5-(...)
Affinity DataKi:  196nMAssay Description:Displacement of SST14 from human recombinant SST5 receptor expressed in CHO cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311348(N-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-yl)-5-(...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of SST14 from human recombinant SST3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311348(N-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-yl)-5-(...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of SST14 from human recombinant SST4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50311348(N-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-yl)-5-(...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of SST14 from human recombinant SST2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed