BDBM50311517 (R,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-azacyclododec-8-en-6-yl)acetamide::CHEMBL1080988

SMILES Clc1ccc(CNC(=O)C[C@H]2C\C=C\CCC(=O)OCCNC2=O)cc1

InChI Key InChIKey=PIGMXBSUAPIWMM-UHFFFAOYSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311517   

TargetSonic hedgehog protein(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311517((R,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-aza...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50311517((R,E)-N-(4-chlorobenzyl)-2-(5,12-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed