BDBM50311546 5-fluoro-2-(1-(6-(4-methoxyphenoxy)pyrimidin-4-yl)piperidin-4-yloxy)pyrimidin-4-amine::CHEMBL1079770

SMILES COc1ccc(Oc2cc(ncn2)N2CCC(CC2)Oc2ncc(F)c(N)n2)cc1

InChI Key InChIKey=JGIUHGMJISMBTR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311546   

TargetDeoxycytidine kinase(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311546(5-fluoro-2-(1-(6-(4-methoxyphenoxy)pyrimidin-4-yl)...)
Affinity DataEC50:  890nMAssay Description:Inhibition of dCK in human CCRF-CEM assessed as inhibition of Ara-C phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetDeoxycytidine kinase(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311546(5-fluoro-2-(1-(6-(4-methoxyphenoxy)pyrimidin-4-yl)...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed