BDBM50311559 2-(1-(6-(4-chloro-2-methylphenoxy)pyrimidin-4-yl)piperidin-4-yloxy)-5-fluoropyrimidin-4-amine::CHEMBL1081544

SMILES Cc1cc(Cl)ccc1Oc1cc(ncn1)N1CCC(CC1)Oc1ncc(F)c(N)n1

InChI Key InChIKey=BQSRSVIDXMZSEP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311559   

TargetDeoxycytidine kinase(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311559(2-(1-(6-(4-chloro-2-methylphenoxy)pyrimidin-4-yl)p...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetDeoxycytidine kinase(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311559(2-(1-(6-(4-chloro-2-methylphenoxy)pyrimidin-4-yl)p...)
Affinity DataEC50:  27nMAssay Description:Inhibition of dCK in human CCRF-CEM assessed as inhibition of Ara-C phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed