BDBM50311641 9-(2,3-difluorobenzyl)-2-(6-fluoro-1H-benzo[d]imidazol-1-yl)-7H-purin-8(9H)-one::CHEMBL1081846

SMILES Fc1ccc2ncn(-c3ncc4[nH]c(=O)n(Cc5cccc(F)c5F)c4n3)c2c1

InChI Key InChIKey=QXLJDDRYEUTLQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311641   

TargetTyrosine-protein kinase JAK3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311641(9-(2,3-difluorobenzyl)-2-(6-fluoro-1H-benzo[d]imid...)
Affinity DataIC50: 108nMAssay Description:Inhibition of human JAK3 (508-1124) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311641(9-(2,3-difluorobenzyl)-2-(6-fluoro-1H-benzo[d]imid...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human JAK2 (532-1132) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed