BDBM50311647 (+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(5-fluorochroman-4-yl)-7H-purin-8(9H)-one::CHEMBL1079526

SMILES Fc1cccc2OCCC(c12)n1c2nc(ncc2[nH]c1=O)-n1cnc2ccccc12

InChI Key InChIKey=GWIYWVOOKZDFBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311647   

TargetTyrosine-protein kinase JAK3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311647((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(5-fluorochro...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human JAK3 (508-1124) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311647((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(5-fluorochro...)
Affinity DataIC50: 97nMAssay Description:Inhibition of human JAK2 (532-1132) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed