BDBM50311652 (+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(8-chlorochroman-4-yl)-7H-purin-8(9H)-one::CHEMBL1081376

SMILES Clc1cccc2C(CCOc12)n1c2nc(ncc2[nH]c1=O)-n1cnc2ccccc12

InChI Key InChIKey=BYARLSXPYJDUIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311652   

TargetTyrosine-protein kinase JAK3(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311652((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(8-chlorochro...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human JAK3 (508-1124) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311652((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(8-chlorochro...)
Affinity DataIC50: 840nMAssay Description:Inhibition of human JAK2 (532-1132) by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed