BDBM50311751 CHEMBL1076192::N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-pyrrolo[3,2-c]pyridin-4-amine

SMILES Cc1cc2c(NCc3c(C)cccc3C)nccc2n1C

InChI Key InChIKey=GQQOBKGSKQCRQT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311751   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311751(N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-pyrrolo[3,2...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311751(N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-pyrrolo[3,2...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311751(N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-pyrrolo[3,2...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311751(N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-pyrrolo[3,2...)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311751(N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-pyrrolo[3,2...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed