BDBM50311755 4-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridin-5-yl)morpholin-3-one::CHEMBL1080982

SMILES Cc1c(C)c2cc(nc(NCc3c(C)cccc3C)c2n1CCO)N1CCOCC1=O

InChI Key InChIKey=XXODNTBQCNWAAG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50311755   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311755(4-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311755(4-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311755(4-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311755(4-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311755(4-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311755(4-(7-(2,6-dimethylbenzylamino)-1-(2-hydroxyethyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed