BDBM50311761 1-(1-allyl-7-(2,6-dimethylbenzylamino)-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridin-5-yl)pyridin-2(1H)-one::CHEMBL1080088

SMILES Cc1c(C)c2cc(nc(NCc3c(C)cccc3C)c2n1CC=C)-n1ccccc1=O

InChI Key InChIKey=AWDJPCNXSYKBPU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311761   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311761(1-(1-allyl-7-(2,6-dimethylbenzylamino)-2,3-dimethy...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311761(1-(1-allyl-7-(2,6-dimethylbenzylamino)-2,3-dimethy...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311761(1-(1-allyl-7-(2,6-dimethylbenzylamino)-2,3-dimethy...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311761(1-(1-allyl-7-(2,6-dimethylbenzylamino)-2,3-dimethy...)
Affinity DataIC50: 500nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311761(1-(1-allyl-7-(2,6-dimethylbenzylamino)-2,3-dimethy...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed